Factor VII
Factor VII
Factor VII (pronounced as "Factor Seven") is one of the proteins that causes blood to clot in the coagulation cascade. It is an enzyme of the serine protease class.
Pronunciation
Factor VII is pronounced as "Factor Seven".
Etymology
The term "Factor VII" is derived from the fact that it is one of several factors identified in the early 20th century as being necessary for blood to clot. The Roman numeral VII was assigned to it in the order of its discovery.
Function
Factor VII is produced in the liver and then released into the bloodstream. When an injury occurs and bleeding begins, Factor VII is activated and begins the process of forming a clot to stop the bleeding. It does this by activating other proteins in the coagulation cascade, including Factor X and Factor IX.
Related Terms
- Coagulation: The process by which blood forms clots.
- Serine protease: A type of enzyme that cuts other proteins.
- Liver: The organ that produces Factor VII.
- Factor X: Another protein in the coagulation cascade that is activated by Factor VII.
- Factor IX: Another protein in the coagulation cascade that can be activated by Factor VII.
Deficiency and Disease
A deficiency of Factor VII can lead to a bleeding disorder known as Factor VII deficiency. This is a rare condition that can lead to excessive bleeding or bruising. It is usually diagnosed through a blood test and can be treated with Factor VII replacement therapy.
External links
- Medical encyclopedia article on Factor VII
- Wikipedia's article - Factor VII
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