Exstrophy

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Exstrophy

Exstrophy (/ɛkˈstrəfi/ ek-STRƏ-fee) is a complex congenital anomaly that involves the urinary bladder and the surrounding structures. The term is derived from the Greek words ex, meaning "out", and strophe, meaning "turning".

Definition

Exstrophy is a rare birth defect of the urinary tract, in which the bladder and associated structures are turned inside out and exposed on the outside of the abdomen. It is part of a spectrum of anomalies known as the Exstrophy-Epispadias Complex.

Symptoms

The most obvious symptom of exstrophy is the visible bladder on the outside of the abdomen. Other symptoms may include a short, wide penis with an exposed urethra in males, or a bifid clitoris and anteriorly displaced vagina in females. There may also be abnormalities of the pelvic bones and spine.

Causes

The exact cause of exstrophy is unknown, but it is thought to occur as a result of a disruption in the development of the urinary tract during the first trimester of pregnancy. It is not believed to be hereditary.

Treatment

Treatment for exstrophy typically involves surgery to close the bladder and reconstruct the genitals. This is usually performed shortly after birth. Long-term management may involve further surgeries, as well as ongoing care to manage urinary and bowel function.

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