Estradiol/drospirenone
Estradiol/Drospirenone
Estradiol/drospirenone (pronunciation: es-tra-DYE-ole/droh-SPIRE-uh-nohn) is a combination medication used in hormone replacement therapy (HRT) for menopausal symptoms.
Etymology
The term "estradiol" is derived from "estrus" (period of fertility for female mammals) and "diol" (a chemical term indicating a certain structure). "Drospirenone" is a synthetic progestin, and its name is derived from its chemical structure.
Usage
Estradiol/drospirenone is primarily used to treat symptoms of menopause such as hot flashes and vaginal dryness. It can also prevent osteoporosis in postmenopausal women and replace estrogen in women with ovarian failure or other conditions that cause a lack of natural estrogen in the body.
Mechanism of Action
Estradiol is a form of estrogen, a female sex hormone produced by the ovaries. It regulates many processes in the body. Drospirenone is a synthetic form of progesterone, another female hormone. It works by preventing the overgrowth of the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.
Related Terms
Side Effects
Common side effects of estradiol/drospirenone may include nausea, vomiting, headache, bloating, breast tenderness, or weight change. Serious side effects can include increased risk of breast cancer, stroke, or dementia.
Precautions
Before taking estradiol/drospirenone, patients should inform their healthcare provider if they have a history of blood clots, liver disease, kidney disease, heart disease, or stroke.
External links
- Medical encyclopedia article on Estradiol/drospirenone
- Wikipedia's article - Estradiol/drospirenone
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