Delamanid
Delamanid
Delamanid (pronunciation: /dɛləˈmænɪd/) is a medicinal drug used in the treatment of tuberculosis. It is specifically used for multi-drug-resistant tuberculosis (MDR-TB) when other treatments are not effective.
Etymology
The term "Delamanid" is derived from its chemical name, Delamanid, which is a derivative of nitro-dihydro-imidazooxazoles.
Usage
Delamanid is used in combination with other anti-tuberculosis medications to treat adults with pulmonary multi-drug resistant tuberculosis (MDR-TB). It is used when an effective treatment regimen cannot otherwise be composed for reasons of resistance or tolerability.
Mechanism of Action
Delamanid inhibits the synthesis of mycolic acid, an essential component of the mycobacterium tuberculosis cell wall. This results in the death of the bacteria and the eventual clearance of the tuberculosis infection.
Side Effects
Common side effects of Delamanid include nausea, vomiting, dizziness, and joint pain. More serious side effects may include QT prolongation and potentially life-threatening arrhythmias.
Related Terms
External links
- Medical encyclopedia article on Delamanid
- Wikipedia's article - Delamanid
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