Chlorotrianisene

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Chlorotrianisene

Chlorotrianisene (pronounced klor-oh-try-an-uh-seen) is a synthetic, non-steroidal estrogen of the triphenylethylene group that is used in menopausal and postmenopausal disorders. It was introduced in 1952 and is no longer in common use.

Etymology

The term "Chlorotrianisene" is derived from its chemical structure, which consists of three phenyl rings (tri-anisene) and a chlorine atom (chloro).

Usage

Chlorotrianisene was primarily used as a form of Hormone Replacement Therapy (HRT) to alleviate symptoms of menopause such as hot flashes and vaginal dryness. It was also used to treat certain types of breast cancer in postmenopausal women.

Side Effects

Like other estrogens, Chlorotrianisene can cause a number of side effects, including nausea, vomiting, breast tenderness, irregular menstrual periods, and weight changes. More serious side effects can include blood clots, stroke, and an increased risk of certain types of cancer.

Related Terms

  • Estrogen: A group of hormones that play an important role in the normal sexual and reproductive development in women.
  • Menopause: The time in a woman's life when menstrual periods permanently stop; it is also called "the change of life."
  • Hormone Replacement Therapy (HRT): Therapy used to supplement the body with either estrogen alone or estrogen and progesterone in combination during and after menopause.
  • Breast Cancer: A type of cancer that forms in the cells of the breasts.

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