Chandler's disease
Chandler's Disease
Chandler's Disease (pronounced: CHAN-dlerz dih-ZEEZ) is a rare, progressive eye condition that primarily affects the cornea and iris of the eye. It is named after the American ophthalmologist, Dr. Paul Chandler, who first described the condition in 1951.
Etymology
The term "Chandler's Disease" is derived from the name of the ophthalmologist who first identified and described the condition. The term "disease" comes from the Old French desaise, meaning "lack of ease", which in medical terms refers to a particular abnormal, pathological condition that affects part or all of an organism.
Definition
Chandler's Disease is a subtype of secondary glaucoma, specifically a form of iridocorneal endothelial syndrome (ICE syndrome). It is characterized by abnormal corneal endothelial cell growth, leading to corneal decompensation, iris atrophy, and secondary glaucoma.
Symptoms
The symptoms of Chandler's Disease can vary but often include blurred vision, pain in the eye, and halos around lights. In some cases, the disease may also cause a noticeable change in the color of the iris.
Diagnosis
Diagnosis of Chandler's Disease is typically made through a comprehensive eye examination, including a detailed examination of the cornea and iris. Additional tests such as gonioscopy, corneal pachymetry, and ocular coherence tomography may also be used to confirm the diagnosis.
Treatment
Treatment for Chandler's Disease primarily focuses on managing the associated glaucoma to prevent further vision loss. This may involve the use of eye drops, oral medications, laser therapy, or surgery. In severe cases, corneal transplantation may be necessary.
Prognosis
The prognosis for individuals with Chandler's Disease varies depending on the severity of the condition and the effectiveness of treatment. With early detection and appropriate treatment, vision loss can often be prevented or slowed.
See Also
External links
- Medical encyclopedia article on Chandler's disease
- Wikipedia's article - Chandler's disease
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