CETP inhibitor
CETP Inhibitor
CETP inhibitors (pronounced as C-E-T-P inhibitors) are a class of drugs that block the function of the Cholesteryl Ester Transfer Protein (CETP). CETP is a plasma protein that plays a crucial role in the reverse transport of cholesterol from peripheral tissues to the liver.
Etymology
The term "CETP inhibitor" is derived from the name of the protein it inhibits, the Cholesteryl Ester Transfer Protein (CETP). The word "inhibitor" is derived from the Latin word "inhibere", which means to restrain or prevent.
Function
CETP inhibitors work by blocking the action of CETP, thereby increasing the levels of High-Density Lipoprotein (HDL) cholesterol, often referred to as "good cholesterol". This is due to the fact that CETP facilitates the transfer of cholesterol from HDL to Low-Density Lipoprotein (LDL) or "bad cholesterol". By inhibiting this process, CETP inhibitors can potentially reduce the risk of atherosclerosis and coronary heart disease.
Related Terms
- Cholesteryl Ester Transfer Protein (CETP): A plasma protein that transfers cholesterol esters from HDL to LDL.
- High-Density Lipoprotein (HDL): Often referred to as "good cholesterol", HDL carries cholesterol from other parts of your body back to your liver.
- Low-Density Lipoprotein (LDL): Often referred to as "bad cholesterol", LDL carries cholesterol particles throughout your body.
- Atherosclerosis: A disease in which plaque builds up inside your arteries.
- Coronary heart disease: A disease that happens when the coronary arteries become narrowed or blocked by cholesterol and fat deposits.
External links
- Medical encyclopedia article on CETP inhibitor
- Wikipedia's article - CETP inhibitor
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