CDAD
CDAD
Clostridioides difficile-associated diarrhea (CDAD) /kloʊˌstrɪdiːˈɔɪdiːz dɪˈfɪsiːl əˈsoʊʃiˌeɪtɪd daɪəˈriːə/ is a type of infectious diarrhea caused by the bacterium Clostridioides difficile (C. diff).
Etymology
The term CDAD is an acronym derived from the name of the bacterium Clostridioides difficile and the condition it causes, "associated diarrhea". Clostridioides difficile was formerly known as Clostridium difficile, with the name change reflecting a reclassification of the bacterium. The term "difficile" is Latin for "difficult", reflecting the bacterium's resistance to early attempts at cultivation.
Symptoms
CDAD is characterized by frequent, watery diarrhea, abdominal pain, and fever. In severe cases, it can lead to life-threatening inflammation of the colon.
Causes
CDAD is caused by an overgrowth of C. difficile bacteria in the colon, often following antibiotic treatment for another infection. The antibiotics disrupt the normal balance of bacteria in the gut, allowing C. difficile to multiply and produce toxins that damage the lining of the colon.
Treatment
Treatment for CDAD typically involves stopping the antibiotic that caused the infection, if possible, and starting a course of antibiotics that are effective against C. difficile. In severe cases, surgery may be required to remove the affected part of the colon.
Related Terms
External links
- Medical encyclopedia article on CDAD
- Wikipedia's article - CDAD
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