CCR5 receptor antagonist
CCR5 Receptor Antagonist
A CCR5 receptor antagonist (pronunciation: /siː siː ɑːr faɪv rɪˈsɛptər æntəˈɡɒnɪst/) is a type of pharmacological agent that inhibits the action of the CCR5 receptor.
Etymology
The term "CCR5 receptor antagonist" is derived from the name of the receptor it inhibits, the CCR5 receptor. "CCR5" stands for "C-C chemokine receptor type 5", a protein found on the surface of white blood cells. The term "antagonist" comes from the Greek word "antagonistes", meaning "opponent" or "rival".
Function
CCR5 receptor antagonists work by blocking the CCR5 receptor, a protein on the surface of certain immune cells. This prevents the HIV virus from entering these cells and causing infection.
Related Terms
- CCR5: A protein on the surface of white blood cells that is involved in the immune system's response to inflammation and infection.
- Chemokine receptor: A type of protein found on the surface of certain cells, which interacts with chemokines to direct the movement of cells.
- Pharmacological agent: A chemical substance used to treat, cure, prevent, or diagnose a disease or to promote well-being.
- HIV: Human Immunodeficiency Virus, a virus that attacks the body's immune system.
Examples
Some examples of CCR5 receptor antagonists include Maraviroc and Vicriviroc, both of which are used in the treatment of HIV infection.
External links
- Medical encyclopedia article on CCR5 receptor antagonist
- Wikipedia's article - CCR5 receptor antagonist
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