Brodifacoum

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Brodifacoum

Brodifacoum (pronounced bro-dih-fa-koom) is a highly lethal rodenticide that is used globally to control rodent populations. It is a member of the 4-hydroxycoumarin anticoagulant class of compounds, which inhibit the vitamin K epoxide reductase enzyme to deplete active vitamin K in the body. This prevents the synthesis of essential blood-clotting factors, leading to uncontrolled bleeding and death in rodents.

Etymology

The term "Brodifacoum" is derived from the chemical name Bromadiolone Difenacoum. Bromadiolone is a potent rodenticide, and Difenacoum is a related anticoagulant. The combination of these two substances results in Brodifacoum, a highly effective rodenticide.

Usage

Brodifacoum is used in many countries to control rodent populations. It is often used in situations where resistance to other anticoagulant rodenticides has been detected. Brodifacoum is typically used in bait form, which is consumed by rodents. The substance is slow-acting, allowing rodents to continue feeding on the bait over a period of time before succumbing to its effects.

Health Effects

Exposure to Brodifacoum can lead to severe health effects in humans and non-target animals. Symptoms of poisoning include uncontrolled bleeding, bruising, anemia, and in severe cases, death. Treatment typically involves the administration of vitamin K1, which can reverse the effects of the anticoagulant.

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