Basophilic stippling
Basophilic Stippling (pronunciation: ba·so·phil·ic stip·pling, /ˌbæsəʊˈfɪlɪk ˈstɪplɪŋ/) is a term used in hematology to describe the presence of small, blue-black granules that are dispersed throughout the cytoplasm of a red blood cell (RBC). These granules are remnants of ribosomal RNA and are seen in various conditions, including lead poisoning, thalassemia, and anemia.
Etymology
The term "basophilic" is derived from the Greek words "basis" which means "base" and "philos" which means "loving". This refers to the property of these granules to stain with basic (blue) dyes. "Stippling" refers to the pattern of tiny spots or specks seen in the RBCs.
Related Terms
- Anisocytosis: Variation in the size of RBCs.
- Poikilocytosis: Variation in the shape of RBCs.
- Hypochromia: Reduced staining intensity of RBCs, indicating less hemoglobin content.
- Microcytosis: Presence of smaller than normal RBCs.
- Macrocytosis: Presence of larger than normal RBCs.
See Also
External links
- Medical encyclopedia article on Basophilic stippling
- Wikipedia's article - Basophilic stippling
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