Ancestim

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Ancestim

Ancestim (pronounced: an-ces-tim) is a recombinant human stem cell factor, also known as SCF or c-kit ligand. It is a growth factor that has been shown to stimulate the proliferation and differentiation of hematopoietic progenitor cells in vitro and in vivo.

Etymology

The term "Ancestim" is derived from the English word "ancestor", referring to its role in the development of cells, and the suffix "-stim", short for "stimulation", indicating its function as a stimulant for cell growth and differentiation.

Function

Ancestim is a crucial component in the body's hematopoietic system, which is responsible for the formation of blood cellular components. It binds to the c-kit receptor on the surface of hematopoietic stem cells and progenitor cells, stimulating their proliferation and differentiation into various types of blood cells.

Clinical Use

In clinical settings, Ancestim is used to stimulate the growth of stem cells in patients undergoing bone marrow transplantation. It is also used in the treatment of certain types of cancer, such as leukemia and lymphoma, where it helps to restore the patient's blood cell counts following chemotherapy or radiation therapy.

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