Alpha-adrenergic receptors
Alpha-adrenergic receptors
Alpha-adrenergic receptors (pronounced: al-fa ad-ren-er-gic re-cep-tors), also known as α-adrenergic receptors or alpha receptors, are a type of adrenergic receptor that have norepinephrine and epinephrine as their endogenous ligands.
Etymology
The term "alpha-adrenergic receptors" is derived from the Greek letter "alpha" (α), used here as a classification, and "adrenergic", which refers to the action of the neurotransmitters adrenaline (epinephrine) and noradrenaline (norepinephrine) on the receptors.
Types
There are two types of alpha-adrenergic receptors, known as alpha-1 and alpha-2, each with different functions and locations in the body.
- Alpha-1 adrenergic receptors (α1) are found in the smooth muscles of the vascular system, where they mediate vasoconstriction.
- Alpha-2 adrenergic receptors (α2) are located in the central and peripheral nervous system and play a role in inhibiting the release of norepinephrine.
Function
Alpha-adrenergic receptors play a crucial role in regulating physiological functions such as blood pressure, heart rate, and the fight-or-flight response. They are also involved in various pathological conditions, including hypertension, heart failure, and psychiatric disorders.
Related Terms
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