Adoptive cell transfer
Adoptive cell transfer (pronounced: a-dop-tive cell trans-fer) is a form of cancer treatment that uses the body's own immune system to fight cancer. The process involves the extraction of immune cells from a patient, modifying them in a laboratory to enhance their ability to attack cancer cells, and then reintroducing them into the patient's body.
Etymology
The term "adoptive cell transfer" is derived from the process itself. "Adoptive" refers to the adoption of modified cells by the body, "cell" refers to the immune cells used in the treatment, and "transfer" refers to the reintroduction of these cells into the patient's body.
Procedure
The procedure for adoptive cell transfer involves several steps. First, immune cells, specifically T cells, are extracted from the patient. These cells are then modified in a laboratory to enhance their ability to recognize and attack cancer cells. This is often done through a process known as gene therapy, where a virus is used to insert a new gene into the T cells. This new gene codes for a receptor that can recognize a specific protein found on the patient's cancer cells. Once the T cells have been modified, they are multiplied in the lab to create a large number of them. These cells are then reintroduced into the patient's body through an infusion.
Related Terms
See Also
External links
- Medical encyclopedia article on Adoptive cell transfer
- Wikipedia's article - Adoptive cell transfer
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