ABCB5
ABCB5
ABCB5 (pronounced as A-B-C-B-five), also known as ATP-binding cassette sub-family B member 5, is a protein that in humans is encoded by the ABCB5 gene.
Etymology
The term ABCB5 is an acronym derived from ATP-Binding Cassette B sub-family member 5. The ATP-binding cassette (ABC) transporters form a large family of proteins, which have a common structure and mechanism of action. They are named for their ability to bind and hydrolyze ATP.
Function
ABCB5 is a member of the ABC transporters, a group of integral membrane proteins that actively transport various compounds across extracellular and intracellular membranes. ABCB5 is a transporter protein that has been shown to confer multidrug resistance to cancer cells. In addition to its role in drug resistance, ABCB5 is also known to play a role in cellular processes such as proliferation, differentiation, and apoptosis.
Related Terms
- ATP-binding cassette transporter
- Multidrug resistance
- Apoptosis
- Cell proliferation
- Cell differentiation
See Also
External links
- Medical encyclopedia article on ABCB5
- Wikipedia's article - ABCB5
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