5-Iodowillardiine

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5-Iodowillardiine

5-Iodowillardiine (pronunciation: 5-eye-oh-doh-will-ar-deen) is a synthetic analogue of willardiine, a naturally occurring amino acid. It is used primarily in scientific research as a selective agonist for the AMPA receptor and kainate receptor, two types of ionotropic glutamate receptors.

Etymology

The term "5-Iodowillardiine" is derived from the name of its parent compound, willardiine, with the prefix "5-Iodo-" indicating the addition of an iodine atom at the 5th position of the willardiine molecule.

Usage

5-Iodowillardiine is used in neuroscience research to study the function and pharmacology of AMPA and kainate receptors. By selectively activating these receptors, researchers can investigate their role in neurotransmission, synaptic plasticity, and neurodegenerative diseases.

Related Terms

  • Willardiine: The parent compound of 5-Iodowillardiine.
  • AMPA receptor: A type of ionotropic glutamate receptor that 5-Iodowillardiine selectively activates.
  • Kainate receptor: Another type of ionotropic glutamate receptor that 5-Iodowillardiine selectively activates.
  • Ionotropic glutamate receptor: A class of receptors that includes the AMPA and kainate receptors.
  • Neurotransmission: The process by which signals are transmitted in the nervous system, which can be studied using 5-Iodowillardiine.
  • Synaptic plasticity: The ability of synapses to strengthen or weaken over time, which can be affected by the activation of AMPA and kainate receptors.
  • Neurodegenerative disease: A type of disease that involves the progressive loss of structure or function of neurons, which can be studied using 5-Iodowillardiine.

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