Dejerine–Roussy syndrome

Dejerine–Roussy syndrome
Synonyms	Thalamic pain syndrome
Pronounce	N/A
Specialty	N/A
Symptoms	Chronic pain, sensory loss, allodynia, dysesthesia
Complications	Depression, anxiety, sleep disturbances
Onset	Typically after a stroke affecting the thalamus
Duration	Long-term, often chronic
Types	N/A
Causes	Stroke, thalamic infarction
Risks	Hypertension, diabetes mellitus, hyperlipidemia, smoking
Diagnosis	Clinical diagnosis, neuroimaging
Differential diagnosis	Central post-stroke pain, peripheral neuropathy, complex regional pain syndrome
Prevention	N/A
Treatment	Pain management, antidepressants, anticonvulsants, physical therapy
Medication	N/A
Prognosis	Variable, often chronic pain
Frequency	Rare
Deaths	N/A

Dejerine–Roussy syndrome (also known as thalamic pain syndrome, or central post-stroke pain) is a condition developed after a stroke at the level of the thalamus. The syndrome is named after two French neurologists, Joseph Jules Dejerine and Gustave Roussy, who first described the condition in 1906.

Symptoms

The main symptom of Dejerine–Roussy syndrome is chronic pain, which can be severe and is often resistant to treatment. The pain is typically on one side of the body and can be described as burning, aching, or pricking. Other symptoms can include sensory loss, hemiparesis (weakness on one side of the body), and hemianesthesia (loss of sensation on one side of the body).

Causes

Dejerine–Roussy syndrome is caused by a lesion in the thalamus, the part of the brain that relays sensory and motor signals to the cerebral cortex. This can occur as a result of a stroke, brain injury, or brain tumor.

Diagnosis

Diagnosis of Dejerine–Roussy syndrome is based on the patient's symptoms and medical history. Imaging tests such as MRI or CT scan may be used to confirm the presence of a thalamic lesion.

Treatment

Treatment for Dejerine–Roussy syndrome is focused on managing the chronic pain. This can include medications such as antidepressants, anticonvulsants, and opioids. In some cases, non-drug treatments such as physical therapy, occupational therapy, and cognitive behavioral therapy may be beneficial.

Prognosis

The prognosis for Dejerine–Roussy syndrome varies. Some patients may experience a reduction in pain over time, while others may continue to experience chronic pain despite treatment.

See also

• Thalamus
• Stroke
• Chronic pain

References

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