Sequestration

Sequestration refers to the process of isolating or separating a substance or object. In the context of medicine, sequestration often refers to the isolation of cells, tissues, or organs within the body due to various conditions or diseases.

Medical Sequestration

In medicine, sequestration can occur in various forms and can affect different parts of the body. It is often associated with conditions such as sickle cell disease, pulmonary sequestration, and splenic sequestration.

Sickle Cell Disease

In sickle cell disease, sequestration crisis can occur when sickle-shaped red blood cells block blood vessels in the spleen, causing a sudden, painful enlargement. This is a medical emergency and can be life-threatening if not treated promptly.

Pulmonary Sequestration

Pulmonary sequestration is a rare congenital condition where a piece of lung tissue is not connected to the bronchial airway system or the pulmonary arterial blood supply. This sequestered lung tissue receives its blood supply from an anomalous systemic artery.

Splenic Sequestration

Splenic sequestration is a severe complication of sickle cell disease, where a large number of sickle cells get trapped in the spleen, causing it to suddenly enlarge. This can lead to a rapid drop in hemoglobin levels, shock, and can be fatal if not treated immediately.

See Also

• Sickle cell disease
• Pulmonary sequestration
• Splenic sequestration

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