Satellite cell
Satellite Cell
Satellite cells (pronounced: /ˈsætəlaɪt sɛl/) are a type of stem cell that remain dormant under normal conditions but can be activated upon injury or during exercise. They are also known as myogenic progenitor cells and are located in the muscle tissue, specifically in the basal lamina of myofibers.
Etymology
The term "satellite cell" was coined in 1961 by Alexander Mauro, due to their location on the periphery of the muscle fibers, similar to how satellites orbit around the earth.
Function
Satellite cells play a crucial role in muscle repair and regeneration. Upon activation, they proliferate and differentiate into myoblasts, which then fuse with damaged muscle fibers to form new myotubes or repair existing ones. This process is regulated by various growth factors and cytokines.
Related Terms
- Myogenesis: The formation of muscular tissue, particularly during embryonic development.
- Muscle hypertrophy: The growth and increase in size of muscle cells.
- Muscle atrophy: The decrease in muscle mass, often due to lack of physical activity or disease.
- Regenerative medicine: A branch of medicine that develops methods to regrow, repair or replace damaged or diseased cells, organs or tissues.
See Also
External links
- Medical encyclopedia article on Satellite cell
- Wikipedia's article - Satellite cell
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