Pyridoxine

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Pyridoxine

Introduction

Pyridoxine, also known as vitamin B6, is one of the vitamins included in the B complex family. It plays a vital role in a wide range of physiological functions, including amino acid metabolism, neurotransmitter synthesis, and hemoglobin production.

Chemical Properties

Pyridoxine is a water-soluble vitamin. Its chemical formula is C8H11NO3, and it exists in several forms, including pyridoxal, pyridoxamine, and pyridoxal phosphate, which is the active coenzyme form.

Dietary Sources

Good dietary sources of pyridoxine include:

  • Poultry, fish, and liver.
  • Starchy vegetables like potatoes.
  • Non-citrus fruits.
  • Fortified cereals and grains.
Various foods high in Pyridoxine.

Biological Functions

Pyridoxine is essential for:

  • Protein and carbohydrate metabolism.
  • The creation of red blood cells and neurotransmitters.
  • Immune function.
  • Brain development during pregnancy and infancy.

Health Benefits

Adequate pyridoxine intake is associated with potential health benefits, including:

  • Reducing the risk of heart disease.
  • Supporting brain health and mood regulation.
  • Alleviating symptoms of premenstrual syndrome (PMS).

Pyridoxine Deficiency

Deficiency of pyridoxine, though rare, can lead to:

  • Anemia.
  • Skin disorders.
  • Neurological symptoms like depression and confusion.
  • Weakened immune function.

Toxicity and Overdose

While pyridoxine is generally safe, excessive intake can lead to neuropathy and other health issues. Supplementation should be monitored, especially for high doses.

Pyridoxine in Medicine

In medical contexts, pyridoxine is used:

  • To treat or prevent pyridoxine deficiency.
  • As a treatment for certain metabolic disorders.
  • To prevent or treat side effects of certain medications like isoniazid.

See Also

References


External Links

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Contributors: Prab R. Tumpati, MD