Sodium picosulfate

Sodium picosulfate is a medication used for the treatment of constipation and for bowel preparation prior to medical procedures. It is a type of laxative, specifically a stimulant laxative, which works by stimulating the muscles in the bowel to move stool through the body.

Etymology

The term "sodium picosulfate" is derived from its chemical composition. "Sodium" refers to the sodium salt form of the drug, "pico" is a prefix in the metric system denoting one trillionth, and "sulfate" refers to the sulfate group present in the chemical structure of the drug.

Medical uses

Sodium picosulfate is used primarily to treat constipation. It is also used for bowel preparation prior to procedures such as colonoscopy or surgery. The medication works by stimulating the muscles in the bowel, which helps to move stool through the body.

Side effects

Common side effects of sodium picosulfate include abdominal cramps, diarrhea, and nausea. In rare cases, it can cause more serious side effects such as electrolyte imbalance and dehydration.

Pharmacology

Sodium picosulfate is a prodrug, which means it is inactive until it is metabolized in the body. It is converted in the colon to its active form, which stimulates the muscles in the bowel to contract and move stool through the body.

History

Sodium picosulfate was first synthesized in the 1960s and has been used as a laxative and for bowel preparation since that time.

See also

• Laxative
• Constipation
• Colonoscopy

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  Sodium picosulfate chemical structure

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