Conjugated estrogens/medroxyprogesterone acetate

Conjugated estrogens/medroxyprogesterone acetate is a combination of estrogen and progestin used in hormone therapy. This combination is used to treat symptoms of menopause such as hot flashes and vaginal changes, and to prevent osteoporosis in postmenopausal women.

Etymology

The term "conjugated estrogens" refers to a mixture of estrogen hormones, while "medroxyprogesterone acetate" is a derivative of progesterone. The term "conjugated" refers to the fact that the estrogens are chemically linked to other substances.

Pharmacology

Conjugated estrogens/medroxyprogesterone acetate works by replacing natural estrogens in a woman who can no longer produce enough estrogen. It works for advanced prostate cancer by antagonizing male hormones.

Side Effects

Common side effects include headache, stomach upset, bloating, dizziness, weight changes, changes in appetite, freckles or darkening of facial skin, increased hair growth, loss of scalp hair, problems with contact lenses, changes in menstrual periods, vaginal itching or discharge, or breast tenderness.

Precautions

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

Interactions

Some products that may interact with this drug include: aromatase inhibitors (such as anastrozole, exemestane), ospemifene, tamoxifen, tizanidine, tranexamic acid, certain combination products used to treat chronic hepatitis C (ombitasvir/paritaprevir/ritonavir with or without dasabuvir).

See Also

• Estrogen
• Progestin
• Hormone therapy
• Menopause
• Osteoporosis