Immune checkpoint inhibitor
| Immune checkpoint inhibitor | |
|---|---|
| Term | Immune checkpoint inhibitor |
| Short definition | immune checkpoint inhibitor (ih-MYOON CHEK-poynt in-HIH-bih-ter) A type of drug that blocks proteins called checkpoints produced by some types of cells in the immune system, such as B. T-cells, and some cancer cells are formed. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
immune checkpoint inhibitor - (pronounced) (ih-MYOON CHEK-poynt in-HIH-bih-ter) A type of drug that blocks proteins called checkpoints produced by some types of cells in the immune system, such as B. T-cells, and some cancer cells are formed. These checkpoints help keep the immune response from getting too strong and can sometimes stop T cells from killing cancer cells. When these checkpoints are blocked, T cells are better able to kill cancer cells. Examples of checkpoint proteins found on T cells or cancer cells are PD-1/PD-L1 and CTLA-4/B7-1/B7-2. Some immune checkpoint inhibitors are used to treat cancer
External links
- Medical encyclopedia article on Immune checkpoint inhibitor
- Wikipedia's article - Immune checkpoint inhibitor
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