Immune checkpoint inhibitor

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Immune checkpoint inhibitor
TermImmune checkpoint inhibitor
Short definitionimmune checkpoint inhibitor (ih-MYOON CHEK-poynt in-HIH-bih-ter) A type of drug that blocks proteins called checkpoints produced by some types of cells in the immune system, such as B. T-cells, and some cancer cells are formed. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


immune checkpoint inhibitor - (pronounced) (ih-MYOON CHEK-poynt in-HIH-bih-ter) A type of drug that blocks proteins called checkpoints produced by some types of cells in the immune system, such as B. T-cells, and some cancer cells are formed. These checkpoints help keep the immune response from getting too strong and can sometimes stop T cells from killing cancer cells. When these checkpoints are blocked, T cells are better able to kill cancer cells. Examples of checkpoint proteins found on T cells or cancer cells are PD-1/PD-L1 and CTLA-4/B7-1/B7-2. Some immune checkpoint inhibitors are used to treat cancer

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