GLP-1
GLP-1
GLP-1 (Glucagon-Like Peptide-1, /ˌɡluːkəˈɡɒn laɪk ˈpeptɪd wʌn/) is a peptide hormone that is secreted by the L cells of the small intestine and colon in response to food intake. It is a potent stimulator of insulin secretion and has several other physiological effects that are beneficial for glucose homeostasis and cardiovascular health.
Etymology
The term GLP-1 is derived from its similarity to the hormone glucagon. Both hormones are produced from the same precursor molecule, proglucagon, but have different effects on the body. The "-1" in GLP-1 refers to the fact that it is one of two major bioactive peptides derived from proglucagon, the other being GLP-2.
Function
GLP-1 has several important functions in the body. It stimulates the pancreas to produce and release insulin, a hormone that helps regulate blood sugar levels. It also inhibits the secretion of glucagon, a hormone that raises blood sugar levels. In addition, GLP-1 slows down the rate at which food leaves the stomach, which helps to control appetite and prevent overeating.
Related Terms
- Insulin: A hormone that regulates the amount of glucose in the blood.
- Glucagon: A hormone that works with insulin to regulate blood sugar levels.
- L cells: Cells in the small intestine and colon that secrete GLP-1.
- Proglucagon: The precursor molecule from which GLP-1 is derived.
- GLP-2: Another peptide hormone derived from proglucagon.
See Also
External links
- Medical encyclopedia article on GLP-1
- Wikipedia's article - GLP-1
This WikiMD article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski