File:Replication stress and its consequences in mitosis.png
From WikiMD's medical encyclopedia
Size of this preview: 412 × 599 pixels. Other resolutions: 165 × 240 pixels | 330 × 480 pixels | 412 × 600 pixels | 528 × 768 pixels | 704 × 1,024 pixels | 2,200 × 3,200 pixels.
Original file (2,200 × 3,200 pixels, file size: 2.48 MB, MIME type: image/png)
Summary
| Description |
English: Replication stress from either endogenous or exogenous causes (red circles) leaves chromosomal segment unreplicated or interwinded leading to anaphase bridges formation. Single-ended DSB could lead to dicentric chromosome formation and thus, also, to anaphase bridge formation. Non-detected damages upon low replicative stress could be grouped in one detectable entity in G1: 53BP1 bodies and/or micronuclei. Replication stress also favors mitotic extra centrosomes and multipolar mitosis, thus amplifying mitotic catastrophes and genome instability to the whole genome.[1] |
| Date | |
| Source | https://doi.org/10.3390/genes6020267 |
| Author | Camille Gelot, Indiana Magdalou, and Bernard S. Lopez |
Licensing
This file is licensed under the Creative Commons Attribution 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 23:05, 24 May 2020 | | 2,200 × 3,200 (2.48 MB) | Rob Hurt | Uploaded a work by Camille Gelot, Indiana Magdalou, and Bernard S. Lopez from https://doi.org/10.3390/genes6020267 with UploadWizard |
File usage
The following page uses this file:
