File:PPARalpha transcriptome.png
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Summary
| Description |
English: Detailed overview map of metabolic genes upregulated by PPARα in mouse liver. The map is based on the published literature combined with transcriptomics analysis of liver of WT and PPARα-/- mice. Colors indicate whether expression of a gene is governed by PPARα during fasting (In green: significantly decreased expression in fasted PPARα-/- mice compared to fasted PPARα+/+ mice), and/or by synthetic PPARα agonists (In blue: significantly increased expression in WT mice treated with Wy14643 or fenofibrate compared to vehicle-treated WT mice). Genes shown in red are upregulated by PPARα during fasting and are upregulated by Wy14643/fenofibrate. |
| Date | |
| Source | Template:Based on published literature |
| Author | Sander Kersten |
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File history
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 07:55, 18 October 2023 | | 3,466 × 2,454 (1.41 MB) | Sander kersten | Update 2023 |
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