\documentclass[12pt,border=1pt,crop,multi=false,tikz,class=scrartcl]{standalone}
\usepackage[T1]{fontenc}
\usepackage[utf8]{inputenc}
\usepackage{chemfig,chemmacros,chemformula}
\usepackage{lmodern}
\usetikzlibrary{decorations.pathmorphing}

\chemsetup[chemformula]{font-shape=sf,format=\sffamily}
\renewcommand*{\familydefault}{\sfdefault}
\renewcommand*\printatom[1]{\ensuremath{\mathsf{#1} } }
\setatomsep{2em}
\setdoublesep{.6ex}
\setarrowdefault{,1,semithick}
\setbondstyle{thick}
%\setarrowlabelsep{1em}

\makeatletter
\begin{document}
\definesubmol\nobond{-[,0.25,,,draw=none]}

%\schemedebug{true}
\schemestart
	\chemfig{*6(-(-N(-[::-60])-[::60])=-=-=-)}
	\arrow{->
		[\scriptsize1.5eq.\hspace{-1.5em}\chemfig{H-[2](=[::60]O)-[::-60](=[::60]O)-[::-60]OEt} \ch{Et2O}, rt.]
		[\scriptsize0.1eq.\hspace{-1em}\chemfig[black!60]{N*5(-(<\ch{"t-Bu"})--O- 
			(-(<[:60])(<:[:120])-[::72]*5(-O--(<:\ch{"t-Bu"})-N=)) =)} \ch{CU(OTf)2}]
	}[,3]
	\chemfig{*6(-(-N(-[::-60])-[::60])=-= (-(-[::60]OH)-[::-60](=[::60]O)-[::-60]OEt) -=-)}
	\hspace{-2em}\parbox{1cm}{\scriptsize78\%\\89\% ee}
\schemestop
\end{document}