Fibrils
Fibrils
Fibrils (/ˈfaɪbrɪlz/), derived from the Latin word fibra meaning fiber, are long, slender, thread-like structures that are often found in various biological organisms. They are a common structural component of many different types of tissues and are essential for their function and integrity.
Structure
Fibrils are typically composed of proteins that are arranged in a highly ordered, repetitive pattern. This structure allows them to provide strength and flexibility to the tissues in which they are found. Some common types of fibrils include collagen fibrils, amyloid fibrils, and reticular fibrils.
Function
The primary function of fibrils is to provide structural support to tissues. They are particularly important in connective tissue, where they help to maintain the shape and integrity of the tissue. In addition, fibrils also play a role in cell adhesion, cell-to-cell communication, and tissue repair.
Related Terms
- Fibrillogenesis: The process by which fibrils are formed.
- Fibrillary: Pertaining to or composed of fibrils.
- Fibrillose: Covered with or having the nature of fibrils.
- Fibrillar: Having a structure or form of a fibril.
Pathology
Abnormalities in the structure or function of fibrils can lead to a variety of diseases. For example, mutations in the genes that encode for the proteins that make up fibrils can lead to diseases such as Ehlers-Danlos syndrome and osteogenesis imperfecta. In addition, the accumulation of abnormal fibrils, such as amyloid fibrils, can lead to diseases such as Alzheimer's disease and Parkinson's disease.
External links
- Medical encyclopedia article on Fibrils
- Wikipedia's article - Fibrils
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