Enclomiphene citrate

Enclomiphene citrate (pronunciation: en-kloh-mi-feen sit-rate) is a pharmaceutical drug used in the treatment of secondary hypogonadism in men. It is a non-steroidal selective estrogen receptor modulator (SERM) that promotes the production of the body's natural testosterone.

Etymology

The term "Enclomiphene" is derived from the Greek words "en" meaning "in", "kloei" meaning "to break", and "phainein" meaning "to show". The "citrate" part of the name refers to the citric acid that the compound is bound to, which aids in its absorption in the body.

Pharmacology

Enclomiphene citrate is a Selective Estrogen Receptor Modulator that increases the production of gonadotropin hormones by inhibiting negative feedback on the hypothalamus. This leads to an increase in the production of testosterone, the primary male sex hormone.

Medical Uses

Enclomiphene citrate is primarily used in the treatment of secondary hypogonadism. It is also being studied for potential use in the treatment of low testosterone levels in men who wish to remain fertile, as it does not affect sperm production like traditional testosterone replacement therapies.

Side Effects

Common side effects of enclomiphene citrate include headache, hot flashes, and nausea. More serious side effects can include visual disturbances and mood changes.

Related Terms

• Clomiphene citrate
• Selective Estrogen Receptor Modulator
• Hypogonadism
• Testosterone

External links

• Medical encyclopedia article on Enclomiphene citrate
• Wikipedia's article - Enclomiphene citrate

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