Digoxin toxicity

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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Digoxin toxicity
File:Digitalis purpurea Koehler drawing.jpg
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	Nausea, vomiting, diarrhea, abdominal pain, confusion, visual disturbances, arrhythmias
Complications	Cardiac arrest, ventricular fibrillation, atrial tachycardia
Onset	Acute or chronic
Duration	Variable
Types	N/A
Causes	Overdose of digoxin or digitalis
Risks	Kidney failure, hypokalemia, hypomagnesemia, hypercalcemia, drug interactions
Diagnosis	Electrocardiogram, serum digoxin level, electrolyte panel
Differential diagnosis	Acute coronary syndrome, hyperkalemia, hypokalemia, hypomagnesemia, hypercalcemia
Prevention	Monitoring of serum digoxin levels, renal function, and electrolytes
Treatment	Activated charcoal, digoxin-specific antibody fragments, electrolyte correction, antiarrhythmic drugs
Medication	Digoxin immune fab
Prognosis	Variable, depending on severity and treatment
Frequency	Rare
Deaths	N/A

Digoxin toxicity is a condition that occurs when you have high levels of the medication digoxin in your body. This can happen if you take too much of the drug at once or if your body has trouble getting rid of it. Digoxin is a type of medication called a cardiac glycoside. It is used to treat certain heart conditions, such as atrial fibrillation and heart failure.

Causes

Digoxin toxicity can be caused by several factors. These include taking too much digoxin, having kidney problems that make it hard for your body to get rid of the drug, and taking certain other medications that can increase your body's digoxin levels.

Symptoms

The symptoms of digoxin toxicity can vary depending on how much of the drug is in your body. They can include nausea, vomiting, diarrhea, abdominal pain, confusion, vision changes, and irregular heartbeat.

Diagnosis

To diagnose digoxin toxicity, your doctor will likely ask about your symptoms and medical history. They may also order blood tests to check your digoxin levels and to see how well your kidneys are working.

Treatment

Treatment for digoxin toxicity usually involves stopping the medication and treating any symptoms. In severe cases, you may need to be hospitalized. Your doctor may also give you a medication called digoxin immune fab, which can help remove the drug from your body.

Prevention

To help prevent digoxin toxicity, it's important to take the medication exactly as your doctor prescribes. You should also have regular check-ups to monitor your digoxin levels and kidney function.

Images

• Symptoms of digoxin toxicity
  Symptoms of digoxin toxicity
• Digibind, an antidote for digoxin toxicity
  Digibind, an antidote for digoxin toxicity

See also

• Cardiac glycoside
• Atrial fibrillation
• Heart failure