Young's syndrome

Young's syndrome
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Young's syndrome, also known as azoospermia sinopulmonary infections, sinusitis-infertility syndrome and Barry-Perkins-Young syndrome, is a rare condition that encompasses a combination of syndromes such as bronchiectasis, rhinosinusitis and reduced male fertility.<ref>,

 Young's syndrome. Obstructive azoospermia and chronic sinopulmonary infections, 
 N. Engl. J. Med., 
 
 Vol. 310(Issue: 1),
 pp. 3–9,
 DOI: 10.1056/NEJM198401053100102,
 PMID: 6689737,</ref><ref>Young syndrome at NIH's Office of Rare Diseases

</ref><ref name=GP>Young's syndrome - General Practice Notebook</ref> In individuals with this syndrome the functioning of the lungs is usually normal but the mucus is abnormally viscous. The reduced fertility ([obstructive [azoospermia]]) is due to functional obstruction of sperm transport down the genital tract at the epididymis, where the sperm is found in viscous, lipid-rich fluid.<ref name=GP/><ref>Definition: Young syndrome from Online Medical Dictionary</ref> The syndrome was named after Donald Young,<ref>,

 Obituary of Donald Herron Young, 
 BMJ, 
 
 Vol. 326(Issue: 7382),
 pp. 226,
 DOI: 10.1136/bmj.326.7382.226/g,
 
 PMC: 1125087,
 
 Full text,</ref> the urologist who first made observations of the clinical signs of the syndrome in 1972.<ref>Online Mendelian Inheritance in Man (OMIM) Young syndrome -279000

</ref>

See also

• Infertility
• Cystic fibrosis

References

• ,

 Young's syndrome. An association between male sterility and bronchiectasis, 
 West. J. Med., 
 
 Vol. 144(Issue: 6),
 pp. 744–6,
 
 PMID: 3727536,
 PMC: 1306774,

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