Acetic acid (medical use)
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Acetic Acid (Medical Use)
Acetic acid is a chemical compound with the formula CH_COOH. It is a colorless liquid with a distinctive sour taste and pungent smell. In the medical field, acetic acid is used for various purposes, including as an antiseptic and in the treatment of infections.
Medical Applications
Antiseptic
Acetic acid is used as an antiseptic to treat infections caused by bacteria and fungi. It is particularly effective against Pseudomonas aeruginosa, a common pathogen in hospital-acquired infections. The acid's low pH creates an environment that is hostile to microbial growth, making it useful for cleaning wounds and preventing infection.
Otitis Externa
In the treatment of otitis externa, also known as swimmer's ear, acetic acid is used in the form of ear drops. The acidic environment helps to inhibit the growth of bacteria and fungi in the ear canal, providing relief from symptoms and promoting healing.
Vaginal Infections
Acetic acid is also used in the treatment of bacterial vaginosis and other vaginal infections. It helps to restore the natural acidity of the vagina, which can be disrupted by infections, thus aiding in the re-establishment of normal flora.
Cervical Cancer Screening
In some low-resource settings, acetic acid is used in visual inspection with acetic acid (VIA) for cervical cancer screening. The application of acetic acid to the cervix causes abnormal cells to turn white, allowing for visual identification of potential precancerous lesions.
Mechanism of Action
Acetic acid works primarily by lowering the pH of the environment, which inhibits the growth of many pathogens. Its ability to disrupt cell membranes and denature proteins also contributes to its antimicrobial properties.
Safety and Side Effects
While acetic acid is generally safe for medical use, it can cause irritation and burning sensations when applied to sensitive tissues. Care should be taken to use the appropriate concentration, as higher concentrations can cause chemical burns.
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Contributors: Prab R. Tumpati, MD