Ace inhibitor

Ace inhibitor

Ace inhibitor (pronounced as /eɪs ɪnˈhɪbɪtər/), also known as Angiotensin-converting enzyme inhibitors, are a class of medication used primarily for the treatment of hypertension and heart failure. They work by causing relaxation of blood vessels as well as a decrease in blood volume, which leads to lower blood pressure and decreased oxygen demand from the heart.

Etymology

The term "Ace inhibitor" is derived from the full name Angiotensin-converting enzyme inhibitor. Angiotensin is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure. It is part of the Renin–angiotensin system, which is a major target for drugs that lower blood pressure. An inhibitor is a substance that slows down or prevents a particular chemical reaction.

Usage

Ace inhibitors are used to treat a number of cardiovascular conditions including:

• Hypertension
• Heart failure
• Myocardial infarction
• Diabetic nephropathy

Related Terms

• Angiotensin II receptor blocker (ARBs)
• Renin inhibitor
• Calcium channel blocker
• Beta blocker

Side Effects

Like all medications, Ace inhibitors can have side effects. These may include:

• Cough
• High potassium levels
• Low blood pressure
• Dizziness
• Headache
• Fatigue
• Nausea

See Also

• Pharmacology
• Cardiology
• Nephrology

External links

• Medical encyclopedia article on Ace inhibitor
• Wikipedia's article - Ace inhibitor

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