ADA-SCID

ADA-SCID
Term	ADA-SCID
Short definition	ADA-SCID - A rare, inherited condition in which the immune system is compromised, resulting in a complete deficiency of B lymphocytes and T lymphocytes (types of white blood cells that help the body fight infection). People with ADA-SCID are at high risk of developing life-threatening viral, bacterial, and fungal infections, as well as certain types of cancer.
Type	Cancer terms
Specialty	Oncology
Language	English
Source	NCI
Comments

ADA-SCID - A rare, inherited condition in which the immune system is compromised, resulting in a complete deficiency of B lymphocytes and T lymphocytes (types of white blood cells that help the body fight infection). People with ADA-SCID are at high risk of developing life-threatening viral, bacterial, and fungal infections, as well as certain types of cancer. Signs and symptoms of ADA-SCID usually appear before 6 months of age and include severe lung infections, chronic diarrhea, skin rashes, and slow growth and development. When symptoms start later in life, they are usually milder. ADA-SCID is caused by mutations (changes) in the ADA gene. The ADA gene produces an enzyme called adenosine deaminase that helps protect lymphocytes from harmful substances in the body. Also called severe combined immunodeficiency with adenosine deaminase deficiency

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