5-MeO-AMT

5-MeO-AMT

Chemical structure of 5-MeO-AMT

3D model of 5-MeO-AMT

5-MeO-AMT (5-methoxy-alpha-methyltryptamine) is a potent psychedelic compound belonging to the tryptamine class. It is known for its psychoactive effects and has been used both recreationally and in research settings.

Chemical Properties

5-MeO-AMT is a derivative of alpha-methyltryptamine (AMT) with a methoxy group at the 5-position of the indole ring. Its chemical formula is C₁₂H₁₈N₂O, and it has a molecular weight of 206.29 g/mol.

Pharmacology

5-MeO-AMT acts primarily as a serotonin receptor agonist, particularly at the 5-HT_2A receptor, which is believed to be responsible for its psychedelic effects. It may also interact with other serotonin receptors, contributing to its complex pharmacological profile.

Effects

The effects of 5-MeO-AMT can vary significantly depending on the dose and individual sensitivity. Common effects include altered perception of time and space, visual and auditory hallucinations, and changes in mood and thought patterns. Some users report intense euphoria, while others may experience anxiety or confusion.

Dosage and Administration

5-MeO-AMT is typically administered orally, but it can also be taken via other routes such as insufflation. The active dose range is generally between 1-5 mg, with effects lasting from 8 to 12 hours. Due to its potency, precise dosing is crucial to avoid adverse effects.

Safety and Toxicity

The safety profile of 5-MeO-AMT is not well-established, and its use carries potential risks. Overdose can lead to severe side effects, including nausea, vomiting, agitation, and cardiovascular complications. Users are advised to exercise caution and avoid combining it with other substances.

Legal Status

The legal status of 5-MeO-AMT varies by country. In some jurisdictions, it is classified as a controlled substance, making its possession, sale, or use illegal. In others, it may be unscheduled but still subject to regulation under analog laws.

Related Compounds

5-MeO-AMT is structurally related to other tryptamines such as 5-MeO-DMT and DMT, which also have psychedelic properties. These compounds share similar mechanisms of action but differ in potency, duration, and subjective effects.

Related Pages

• Psychedelic drug
• Tryptamine
• Serotonin receptor
• 5-MeO-DMT

Gallery

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  5-MeO-AMT sample

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  5-MeO-AMT sample from DEA

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  5-MeO-AMT chemical structure

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  3D stick model of 5-MeO-AMT

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  5-MeO-AMT check

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  5-MeO-AMT sample