Androstenol

From WikiMD's medical encyclopedia

(Redirected from 5α-Androst-16-en-3α-ol)

Androstenol is a naturally occurring steroidal pheromone found in humans and other mammals. It is a derivative of testosterone and is known for its role in influencing social and sexual behavior.

Chemical Structure

Androstenol is a type of steroid with the chemical formula C19H30O. It is characterized by its hydroxyl group at the 3_ position, which distinguishes it from other related compounds such as androstenone. The structure of androstenol is depicted in the image to the right.

Biological Function

Androstenol is primarily known for its function as a pheromone. In humans, it is believed to influence social behavior and sexual attraction. It is secreted in sweat and is thought to play a role in olfactory communication among individuals.

Pheromonal Effects

In various studies, androstenol has been shown to affect the perception of attractiveness and approachability. It is often associated with a "musky" scent and is thought to enhance interpersonal communication by modulating mood and perception.

Sources and Synthesis

Androstenol is synthesized in the body from cholesterol through a series of enzymatic reactions. It is produced in the adrenal glands, gonads, and other tissues. In addition to its endogenous production, androstenol can also be found in certain foods, such as truffles, which are known for their distinctive aroma.

Related Compounds

Androstenol is part of a family of related compounds, including androstenone, androsterone, and androstenedione. These compounds share similar structures and functions but differ in their specific effects and potency as pheromones.

Related Pages

Androstenol

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Contributors: Prab R. Tumpati, MD