Synephrine

Synephrine is a naturally occurring alkaloid that is often used in weight loss supplements due to its purported fat-burning effects. It is found in certain plants and animals, most notably the bitter orange plant (Citrus aurantium).

Overview

Synephrine is chemically similar to the ephedrine and pseudoephedrine found in many over-the-counter cold/allergy medications and in a number of weight loss and energy supplements that contain Ma Huang. Therefore, synephrine shares many of the same properties and effects, acting primarily as a stimulant.

Uses

Synephrine is used in dietary supplements that are marketed to reduce appetite, increase metabolism, and burn fat. It is often used as a substitute for ephedrine in dietary supplements after the Food and Drug Administration (FDA) banned products containing ephedrine alkaloids in 2004.

Safety and Side Effects

The safety of synephrine is a matter of debate. While some studies suggest that it is safe when used as directed, others suggest that it can lead to high blood pressure, fainting, heart attack, stroke, and other severe side effects, especially when taken with other stimulants.

See Also

• Ephedrine
• Pseudoephedrine
• Food and Drug Administration
• Alkaloid
• Weight loss

References

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