Hydroxyethyl starch-induced pruritus

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Hydroxyethyl starch-induced pruritus is an intense itching, lasting for as long as one year, occurring following hydroxyethyl starch intravenous infusion for vascular insufficiency.<ref>Bork K, 

 Pruritus precipitated by hydroxyethyl starch: a review, 
 British Journal of Dermatology, 
 2005,
 Vol. 152(Issue: 1),
 pp. 3–12,
 DOI: 10.1111/j.1365-2133.2004.06272.x,
 PMID: 15656795,</ref><ref name="Fitz2">Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.</ref>: 401  There is no treatment for  the itch.

An updated clinical review on storage in different tissues describes a pattern of storage in the reticuloendothelial system and also the skin (Wiedermann). Differential storage described via immuno-electron microscopy, see Ständer 2001 below.

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References

Further reading

  • ,
 Accumulation of hydroxyethyl starch in human and animal tissues: a systematic review, 
 Intensive Care Med, 
 2014,
 Vol. 40(Issue: 2),
 pp. 160–70,
 DOI: 10.1007/s00134-013-3156-9,
 PMID: 24257970,
  • ,
 Differential storage of hydroxyethyl starch (HES) in the skin: an immunoelectron-microscopical long-term study, 
 Cell Tissue Res., 
 2001,
 Vol. 304(Issue: 2),
 pp. 261–9,
 DOI: 10.1007/s004410000324,
 PMID: 11396719,


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    Hydroxyethyl starch-induced pruritus
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