Pernicious

Pernicious Anemia is a type of anemia that occurs when the body is unable to absorb vitamin B12 from the gastrointestinal tract. This condition is also known as Addison's Anemia or Congenital Pernicious Anemia.

Causes

Pernicious Anemia is caused by a lack of intrinsic factor, a protein made in the stomach. This is necessary for the absorption of vitamin B12 from food. Without intrinsic factor, vitamin B12 cannot be absorbed and utilized by the body. This leads to a deficiency of red blood cells, which is known as anemia.

Symptoms

The symptoms of Pernicious Anemia can vary, but they often include fatigue, weakness, and shortness of breath. Other symptoms may include pale or yellowish skin, irregular heartbeats, weight loss, and a sore tongue.

Diagnosis

Diagnosis of Pernicious Anemia typically involves blood tests to check the level of vitamin B12 in the body. Other tests may include a complete blood count (CBC) to check the number and appearance of red blood cells, and a test to measure the level of intrinsic factor antibodies.

Treatment

Treatment for Pernicious Anemia usually involves injections of vitamin B12. These injections are typically given every month. Oral supplements of vitamin B12 may also be recommended for some people.

See Also

• Anemia
• Vitamin B12
• Intrinsic Factor

References

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