Tachykinin receptor 2

Tachykinin receptor 2 (TACR2) is a protein that in humans is encoded by the TACR2 gene. It is one of the three known receptors for the tachykinin family of neuropeptides.

Function

TACR2 is a member of a larger family of G protein-coupled receptors. It is a receptor for neurokinin A, a neuropeptide in the tachykinin family. Neurokinin A is a neurotransmitter involved in various biological processes including pain perception and smooth muscle contraction.

Clinical significance

Alterations in the function or expression of TACR2 have been associated with various diseases, including asthma, irritable bowel syndrome, and migraines. Drugs that block the action of TACR2 may have potential therapeutic uses in these conditions.

See also

• Tachykinin receptor
• Tachykinin receptor 1
• Tachykinin receptor 3

References

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External links

• TACR2 at HUGO Gene Nomenclature Committee
• TACR2 at National Center for Biotechnology Information

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