Haemaccel

Haemaccel is a type of colloid solution used in medicine for fluid resuscitation and volume replacement in patients who have lost blood or fluids due to various medical conditions or surgical procedures. It is commonly used in emergency situations to help stabilize patients who are experiencing hypovolemic shock, a condition characterized by a severe decrease in blood volume.

Composition

Haemaccel is a sterile solution that contains hydroxyethyl starch (HES) as its main active ingredient. HES is a synthetic polymer that is derived from amylopectin, a component of starch. The solution also contains electrolytes such as sodium, chloride, and potassium to help maintain the body's electrolyte balance.

Mechanism of Action

When administered intravenously, Haemaccel works by expanding the volume of blood plasma, which helps to increase blood pressure and improve tissue perfusion. The HES molecules in the solution have a high molecular weight, which allows them to remain in the bloodstream for an extended period of time, effectively increasing the volume of circulating blood.

Indications

Haemaccel is commonly used in the following situations:

• Treatment of hypovolemic shock
• Fluid resuscitation in patients with severe dehydration
• Volume replacement in patients undergoing major surgeries or trauma

Contraindications

Haemaccel should not be used in patients with the following conditions:

• Severe renal impairment
• Severe coagulopathy
• Known hypersensitivity to hydroxyethyl starch or any other component of the solution

Side Effects

Common side effects of Haemaccel may include:

• Fluid overload
• Coagulopathy
• Allergic reactions
• Renal impairment

Administration

Haemaccel is typically administered intravenously by a healthcare professional. The dosage and rate of infusion will vary depending on the patient's condition and fluid requirements.

References

• Colloid
• Hypovolemic shock
• Fluid resuscitation