N-Ethylnorketamine

N-Ethylnorketamine

N-Ethylnorketamine (often abbreviated as NENK) is a dissociative anesthetic that is closely related to ketamine and phencyclidine. It is a derivative of ketamine where the methyl group attached to the nitrogen atom is replaced by an ethyl group.

Chemistry

N-Ethylnorketamine is a member of the class of compounds known as arylcyclohexylamines. These are compounds containing a cyclohexylamine moiety attached to an aryl group. The chemical structure of N-Ethylnorketamine is similar to that of ketamine, with the only difference being the substitution of the methyl group on the nitrogen atom with an ethyl group.

Pharmacology

The pharmacology of N-Ethylnorketamine is not fully understood. However, it is known to act as an NMDA receptor antagonist, similar to other arylcyclohexylamines. This means it blocks the action of the neurotransmitter glutamate at the NMDA receptor, leading to a dissociative or "out of body" state.

Effects

The effects of N-Ethylnorketamine are similar to those of other dissociative anesthetics. These can include feelings of detachment from one's body, hallucinations, and a distorted perception of time and space. However, the intensity and duration of these effects can vary depending on the dose and route of administration.

Legal Status

The legal status of N-Ethylnorketamine varies by country. In some countries, it is a controlled substance, while in others it is legal to possess and use.

See Also

• Ketamine
• Phencyclidine
• Dissociative
• Anesthetic
• NMDA receptor antagonist

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