Macromerine

Macromerine is a naturally occurring phenethylamine and alkaloid. It is found in several species of cacti. While its psychoactive properties are not well-studied, it is known to be a non-selective serotonin receptor agonist.

Chemistry

Macromerine is a phenethylamine, specifically a β-phenethylamine. It is structurally related to other phenethylamine alkaloids such as mescaline and tyramine. Macromerine has a methoxy group at the 3,4,5 positions of the benzene ring.

Natural occurrence

Macromerine is found in several species of cacti, including Coryphantha species such as Coryphantha macromeris and Coryphantha greenwoodii. It is also found in the Dolichothele genus.

Pharmacology

The pharmacology of macromerine is not well-studied. However, it is known to act as a non-selective serotonin receptor agonist. This means it can bind to and activate multiple types of serotonin receptors in the brain. The effects of this on the human body are not well-understood, and further research is needed.

Legal status

The legal status of macromerine varies by country. In some countries, it is controlled under laws regulating psychoactive substances. In others, it is legal to possess and use. Always check local laws before attempting to possess or use macromerine.

See also

• Phenethylamine
• Mescaline
• Coryphantha
• Serotonin receptor

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