Perrottetinene

Perrottetinene is a naturally occurring cannabinoid compound found in the liverwort plant species Radula marginata and Radula perrottetii. It is structurally similar to tetrahydrocannabinol (THC), the active compound in cannabis, and has been found to have similar psychoactive effects in mice.

History

Perrottetinene was first isolated and identified in 1994 by a team of Japanese researchers led by Yoshinori Asakawa. The compound was named after the Swiss botanist G.A.W. Perrottet, who first collected samples of Radula perrottetii in the 19th century.

Structure and properties

Perrottetinene is a terpenoid compound, meaning it is derived from isoprene units. It is structurally similar to THC, with the main difference being the presence of a furan ring instead of a pyran ring. This structural similarity is thought to be responsible for the compound's psychoactive effects.

Biological effects

In 2018, a study published in the journal Science Advances reported that perrottetinene has psychoactive effects in mice. The study found that the compound activates the same cannabinoid receptors in the brain as THC, and has anti-inflammatory and analgesic effects. However, the study also noted that the effects of perrottetinene are less potent than those of THC.

Legal status

As of 2021, perrottetinene is not specifically regulated under international drug control conventions. However, it may be considered a controlled substance in some jurisdictions under analogue laws.

See also

• Cannabinoid
• Cannabis (drug)
• Radula marginata
• Radula perrottetii

References

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