Trabecular meshwork

Trabecular meshwork is a part of the eye that helps with the drainage of aqueous humor. It is located near the base of the cornea, and is responsible for maintaining the balance of fluid within the eye. Any damage or blockage to the trabecular meshwork can lead to increased intraocular pressure, which is a risk factor for glaucoma.

Structure

The trabecular meshwork is a spongy, mesh-like structure located in the anterior part of the eye. It is made up of connective tissue and is divided into three parts: the uveal meshwork, the corneoscleral meshwork, and the juxtacanalicular tissue. The uveal meshwork is the closest to the center of the eye, while the corneoscleral meshwork and juxtacanalicular tissue are closer to the periphery.

Function

The primary function of the trabecular meshwork is to facilitate the outflow of aqueous humor from the anterior chamber of the eye. The aqueous humor is a clear fluid that nourishes the cornea and the lens, and its proper drainage is essential for maintaining the intraocular pressure within a normal range. The trabecular meshwork acts as a filter, allowing the aqueous humor to flow out while preventing the passage of larger particles.

Clinical significance

Damage or blockage to the trabecular meshwork can lead to increased intraocular pressure, a condition known as ocular hypertension. This is a major risk factor for the development of glaucoma, a group of eye diseases that can cause vision loss and blindness. In glaucoma, the increased pressure within the eye can damage the optic nerve, which transmits visual information from the eye to the brain.

See also

• Anterior chamber of the eye
• Aqueous humor
• Glaucoma
• Ocular hypertension

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