Valine

Valine is an amino acid that is used in the biosynthesis of protein. It is classified as a branched-chain amino acid (BCAA), along with leucine and isoleucine. Valine is essential amino acid, meaning it cannot be synthesized by the body and must be obtained through the diet.

Structure

Valine is a aliphatic amino acid that is closely related to leucine and isoleucine, both in structure and in function. Its three carbon side chain is branched, making it one of the three branched-chain amino acids.

Function

Valine plays a number of roles in the body. It is involved in muscle metabolism, repair and function, and in the maintenance of proper nitrogen balance in the body. It is also used as an energy source by muscle tissue.

Dietary Sources

Valine is found in a wide variety of foods, including meats, dairy products, mushrooms, soy, peanuts, and grains. It can also be obtained through dietary supplements.

Deficiency and Overdose

Deficiency of valine can lead to symptoms such as maple syrup urine disease (MSUD), which is a rare inherited disorder that affects the body's ability to metabolize certain amino acids. Overdose of valine can lead to symptoms such as hallucinations, and in severe cases, can be life-threatening.

See Also

• Amino acid
• Protein
• Branched-chain amino acid
• Leucine
• Isoleucine

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