Hypofractionated high-dose intensity-modulated radiotherapy

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This is an experimental form of intensity-modulated radiotherapy where higher X-ray dosages are used in fewer fractions (sessions) this is called hypofractionated radiotherapy. Although the dose per fraction is higher than standard radiotherapy, the total dose is lower.<ref name=CHHIP/>

The hope is that it will be as effective but cause less toxicity.<ref name=CHHIP/>

Prostate cancer

One trial<ref>UKCRN Database:Conventional or Hypofractionated High Dose Intensity Modulated Radiotherapy for Prostate Cancer Archived September 27, 2007, at the Wayback Machine</ref> for prostate cancer ran in 2011.<ref name=CHHIP>

A trial comparing different ways of giving radiotherapy for prostate cancer (CHHIP)(link). {{{website}}}.

2015-03-17.



</ref>In 2016 the HYPRO study reported results comparing the use of standard fractionation (39 fractions of 2 Gy for 8 weeks) with hypofractionation (with 19 fractions of 3.4 Gy for 6.5 weeks) among 820 patients with intermediate- or high-risk prostate cancer.<ref name=HYPRO-2>Toxicities May Affect Readiness of Hypofractionation in Prostate Cancer. March 2016</ref>

References


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