Primer

From WikiMD's Wellness Encyclopedia

Revision as of 00:38, 24 February 2024 by Prab (talk | contribs) (CSV import)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

Primer is a molecule, typically a short strand of RNA, that serves as a starting point for DNA synthesis. It is necessary for DNA replication because the enzymes that catalyze this process, DNA polymerases, can only add new nucleotides to an existing strand of DNA.

Function

The main function of a primer is to act as a starting point for DNA synthesis. During DNA replication, the DNA polymerase enzyme can only add new nucleotides to the 3' end of an existing strand of DNA. Therefore, a primer, which is a short strand of RNA, must first bind to the DNA template strand. This provides a 3' end to which the DNA polymerase can add new nucleotides.

Synthesis

Primers are synthesized by an enzyme called primase. Primase is a type of RNA polymerase that creates a short RNA sequence that is complementary to the DNA template strand. This RNA sequence serves as the primer for DNA synthesis.

Role in DNA Replication

During DNA replication, the primer binds to the DNA template strand at the origin of replication. The DNA polymerase then adds new nucleotides to the 3' end of the primer, extending the DNA strand. Once the DNA replication is complete, the RNA primer is removed and replaced with DNA.

See Also

File:WHO Rod.svg
This article is a medical stub. You can help WikiMD by expanding it!
PubMed
Wikipedia
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Ad. Transform your life with W8MD's Budget GLP-1 injections from $49.99


W8MD weight loss doctors team
W8MD weight loss doctors team

W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:

NYC weight loss doctor appointmentsNYC weight loss doctor appointments

Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.

Linkedin_Shiny_Icon Facebook_Shiny_Icon YouTube_icon_(2011-2013) Google plus


Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.