Duodenum

Duodenum is the first part of the small intestine immediately beyond the stomach, leading to the jejunum. It plays a vital role in the digestion of food in the human digestive system.

Anatomy

The duodenum is a C-shaped or horseshoe-shaped structure approximately 10-12 inches long. It is located in the upper abdomen, and the concavity of the horseshoe is where the head of the pancreas is nestled.

Function

The primary function of the duodenum is to continue the process of breaking down food, using enzymes secreted by the pancreas and bile from the liver. The duodenum also regulates the rate of emptying of the stomach via hormonal pathways.

Diseases of the Duodenum

Several diseases can affect the duodenum, including peptic ulcers, duodenitis, and celiac disease.

Peptic Ulcers

Peptic ulcers are sores that develop on the lining of the stomach, upper small intestine or esophagus.

Duodenitis

Duodenitis is inflammation of the duodenum, which can be acute or chronic.

Celiac Disease

Celiac disease is a serious autoimmune disorder that can occur in genetically predisposed people where the ingestion of gluten leads to damage in the small intestine.

See Also

• Small intestine
• Stomach
• Pancreas
• Liver
• Peptic ulcers
• Duodenitis
• Celiac disease

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