Lobomycosis

Lobomycosis (also known as Lobo's disease) is a rare fungal infection that primarily affects the skin and subcutaneous tissues. It is caused by the fungus Lacazia loboi, which is found in tropical and subtropical regions, particularly in Central and South America.

Etiology

Lobomycosis is caused by the fungus Lacazia loboi. This fungus is not found in the environment, but is believed to be transmitted through direct contact with an infected individual or animal, particularly dolphins.

Clinical Presentation

The disease typically presents as keloid-like nodules on the skin, which can coalesce to form plaques. These lesions are usually found on exposed areas of the body, such as the face, ears, and extremities. The disease is chronic and progressive, and can lead to significant disfigurement if left untreated.

Diagnosis

Diagnosis of lobomycosis is based on clinical presentation and histopathological examination of skin biopsy specimens. The fungus Lacazia loboi can be seen in tissue sections as yeast-like cells arranged in chains or clusters.

Treatment

Treatment of lobomycosis is challenging due to the fungus's resistance to most antifungal drugs. Surgical excision of the lesions is often the treatment of choice. In some cases, antifungal drugs such as itraconazole or clofazimine may be used.

Epidemiology

Lobomycosis is endemic in certain regions of Central and South America, particularly in the Amazon basin. It is also seen in dolphins, which are believed to be a reservoir for the disease.

See Also

• Mycosis
• Tropical medicine
• Dermatology

References

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